The ZEISS INTRABEAM 600 is a precise intraoperative radiotherapy system that delivers low-energy X-ray treatment directly to the tumor bed during surgery. Its focused 50 kV source minimizes scatter, protecting healthy tissues while providing effective localized irradiation. The system supports multiple applicator types for breast, brain, spine, gastrointestinal, and skin cancer procedures. By integrating surgery and radiation in one session, it reduces postoperative treatment needs, enhances workflow efficiency, and supports personalized, patient-centered care guided by strong clinical evidence.