ROSA ONE Brain is a versatile robotic system built specifically for stereotactic neurosurgery. Its 6-degree-of-freedom robotic arm provides precise trajectory alignment for procedures such as SEEG, DBS, biopsies, and endoscopic interventions. The platform supports multiple registration methods, flexible patient positioning, and stable head fixation without the need for intra-procedure repositioning. Surgeons benefit from an intuitive interface with integrated force-torque sensing and dedicated planning software that enables preoperative trajectory design. By improving speed, accuracy, and minimally invasive access, ROSA ONE Brain streamlines neurosurgical workflows while reducing procedural complexity.