The PRISMAFLEX System is an advanced platform engineered for continuous renal replacement therapy in critically ill patients. Designed for flexibility, it supports multiple CRRT modalities and therapeutic plasma exchange without the need for additional equipment. Its automation features provide immediate visual feedback and precise fluid balance, helping clinicians focus on patient care rather than device management. With integrated EMR connectivity, the system reduces manual documentation and streamlines workflows. Suitable for patients weighing greater than 20 kilograms, PRISMAFLEX ensures consistent delivery of metabolic control, fluid management and electrolyte stabilization in demanding critical care environments.