The AlphaVac System is a percutaneous mechanical thrombectomy device designed for controlled clot removal in large vessels, especially for treating acute pulmonary embolism. It uses a proprietary funnel cannula to enhance clot capture and an ergonomic reloadable handle that enables continuous aspiration. Two system configurations, F1885 and F2220/F22180, support different anatomical needs and procedural approaches. The system also provides features such as a hemostatic valve, optimized shaft design, and transparent waste collection. Clinical studies suggest AlphaVac may reduce ICU stays and lower reliance on thrombolytic therapy while improving operator control, navigation, and overall procedural efficiency.